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Alternative Names: Regional Enteritis or Ileitis. Crohn's Disease causes inflammation in the small intestine. Crohn's disease usually occurs in the lower part of the small intestine, called the ileum, but it can affect any part of the digestive tract, from the mouth to the anus. The inflammation can cause pain and can make the intestines empty frequently, resulting in diarrhea. This inflammation of the mucosa can cause diarrhea, which is the most common symptom of IBD, with or without intestinal complications. These diseases are believed to be caused by a combination of genetic and non-genetic, or environmental factors (such as infections) that interact with the body's immune system. The two primary sites for Crohn's disease are the ileum, which is the last portion of the small bowel (ileitis, regional enteritis), and the colon (Crohn's colitis). The condition begins as small, microscopic nests of inflammation which persist and smolder.
Complications Complications include Peritonitis, Gastrointestinal bleeding, Impaired intestinal absorption, Amyloidosis, Arthritis - synovial fluid similar to that of rheumatoid arthritis, but with negative rheumatoid factor, Ankylosing spondylitis. |
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