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| Glomerulonephritis refers to the condition in which the glomeruli (tiny filters in your kidney which help clean the blood) become inflamed and are unable to carry out their filtering functions. The majority of patients have the less aggressive chronic form, which may or may not progress to end-stage renal disease (ESRD) over many years (10 to 25 or more). In the small number of patients who have the rapidly-progressive form, it can lead to ESRD within 5 years. Causes & Development What happens in cases of Glomerulonephritis? In any infection, human body identifies the structure of microorganism as antigen. Against the antigen, body produces antibodies (protective against infection). The antibodies formed against bacteria, viruses mistake glomerulus as foreign material and begin to attack it. This is one type of glomerulonephritis. Signs & Symptoms There are usually no visible symptoms, and the patient is totally unaware that anything is wrong. Particularly amongst adults, the blood is first detected in the urine during a routine medical examination (for example work or insurance-related). |
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