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The normal level is approximately 2-7mg/dl. This protection may prevent tissue wear and aging, in addition to other free-radical diseases. Thus, uric acid has a new image as being an important part of balanced human function and not just a waste product. The onset of gout before age 30 in men or before menopause in women is unusual and raises concern about an associated inherited enzyme defect or renal disease. The inflammatory process in gout is unrelated to infection.
Gout is strongly associated with obesity, hypertension, hyperlipidemia, diabetes and dehydration. About 10% of people with hyperuricemia are overproducers of uric acid.
Signs & Symptoms Attacks are usually marked by intermittent joint pain, swelling, redness and warmth. The definitive diagnosis of gout is dependent on finding uric acid crystals in the joint fluid during an acute attack. Additionally, uric acid levels are often elevated in individuals without gout. While sudden swelling and pain in a joint, especially the big toe, suggests the diagnosis of gout, many other arthritic conditions and some infections present themselves in a similar manner. |
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