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| Soybean oil, canola oil and olive oil are good sources of the vitamin, while corn oil and peanut oil are very poor sources. A portion of the body's vitamin K is supplied by bacteria living in the intestine rather than by dietary sources. Three forms of biologically active vitamin K are known, they are menadione, phylloquinone, and menaquinone-7. Not only is vitamin K involved in the synthesis of clotting factors VII, IX, and X; it is also involved in the conversion of pre-prothrombin to prothrombin (the precursor to thrombin), which is important in fibrin blood clot formation. The most common deficiency of vitamin K is at birth since vitamin K does not traverse well through the placenta, nor through breast milk. When needed for the correction of prolonged bleeding due to over-anticoagulation with warfarin, oral vitamin K (1-5mg) was found to be as effective as IV administration, but had a slower onset of action. [Br J Haematol 2001;115(1): pp.145-149]. Counter-Indicators People on any drug that is intended to change the blood clotting time, like coumadin, should contact their physician before taking large amounts of vitamin K. |
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